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Tu1677 Upregulation of Fas Ligand Expression Promotes Colon Cancer Cell Migration and Metastasis In Vitro and In Vivo

✍ Scribed by O'Callaghan, Grace; Reagan, Michaela R.; Flores, Ludmila; Zhang, Yong; Azab, Abdel; Roccaro, Aldo; Shanahan, Fergus; Ghobrial, Irene; Houston, Aileen

Book ID: 122933809
Publisher: Elsevier Science
Year: 2014
Tongue: English
Weight: 65 KB
Volume: 146
Category: Article
ISSN: 0016-5085
DOI: 10.1016/S0016-5085(14)62953-X

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## Abstract Cell migration, which involves acto‐myosin dynamics, cell adhesion, membrane trafficking and signal transduction, is a prerequisite for cancer cell metastasis. Here, we report that an actin‐dependent molecular motor, unconventional myosin Va, is involved in this process and implicated i