High dose tertiary amine tricyclic antid
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A. D. Hodgkiss; P. T. McCarthy; A. N. Sulke; P. K. Bridges
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Article
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1995
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John Wiley and Sons
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English
โ 656 KB
The relationships between dosage, plasma concentration, antidepressant response and toxicity were investigated in 24 highly selected patients with severe, refractory major depression who were prescribed amitriptyline, clomipramine or dothiepin at high dosage (15C-525 mg/day), usually in combination