𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Tu1172 Reversal of Colonic Hypomethylation as a Common Mechanism of Action of Chemopreventive Agents for Colorectal Cancer

✍ Scribed by Qi, Wentao; Hou, Lifang; Jiang, Hongmei; Kunte, Dhananjay; DeLaCruz, Mart; Gibson, Tina P.; Patel, Amir C.; Stypula, Yolanda E.; Wali, Ramesh K.; Roy, Hemant K.


Book ID
122331116
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
87 KB
Volume
142
Category
Article
ISSN
0016-5085

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Modulation of DNA hypomethylation as a s
✍ Lianhui Tao; Wei Wang; Paula M. Kramer; Ronald A. Lubet; Vernon E. Steele; Micha πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 171 KB

## Abstract Surrogate end‐point biomarkers are being developed as indicators of the efficacy of chemopreventive agents. These biomarkers are molecular and biological end‐points that can be modulated by chemopreventive agents in accordance with their efficacy to prevent cancer. DNA hypomethylation i

Development of difluoromethylornithine a
✍ Frank L. Meyskens Jr.; Eugene W. Gerner πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 406 KB

Experimental studies have demonstrated that carcinogenesis is a multistep process in which inappropriate proliferation of cells is a critical determinant. Polyamines support sustained growth and are highly regulated in all cells. The rate limiting enzyme for this pathway is ornithine decarboxylase (