TT virus levels in the plasma of infected individuals with different hepatic and extrahepatic pathology
✍ Scribed by Mauro Pistello; Antonietta Morrica; Fabrizio Maggi; Maria Linda Vatteroni; Giulia Freer; Claudia Fornai; Francesca Casula; Santino Marchi; Pietro Ciccorossi; Paolo Rovero; Mauro Bendinelli
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 125 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0146-6615
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✦ Synopsis
TT virus (TTV) infection is extremely widespread in the general population. A sensitive real-time PCR assay was developed that quantitated accurately the most prevalent TTV genotypes in Italy. When used to test 217 individuals for TTV viraemia, the overall prevalence was 94%. Viraemia levels varied widely amongst individual subjects, with no major differences related to gender or age. The highest TTV titres were in haemophiliacs and in patients with non-A-E hepatitis, but they did not differ from the group with miscellaneous diseases. HIV- and HCV-infected subjects and patients with primary liver diseases had TTV loads similar to those of healthy individuals.