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TSLP polymorphisms are associated with asthma in a sex-specific fashion

✍ Scribed by G. M. Hunninghake; M. E. Soto-Quirós; L. Avila; H. P. Kim; J. Lasky-Su; N. Rafaels; I. Ruczinski; T. H. Beaty; R. A. Mathias; K. C. Barnes; J. B. Wilk; G. T. O’Connor; W. James Gauderman; H. Vora; J. W. Baurley; F. Gilliland; C. Liang; J. S. Sylvia; B. J. Klanderman; S. S. Sharma; B. E. Himes; C. J. Bossley; E. Israel; B. A. Raby; A. Bush; A. M. Choi; S. T. Weiss; J. C. Celedón

Book ID
110887188
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
589 KB
Volume
65
Category
Article
ISSN
0105-4538

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IL10 is an anti-inflammatory cytokine that has been found to have lower production in macrophages and mononuclear cells from asthmatics. Since reduced IL10 levels may influence the severity of asthma phenotypes, we examined IL10 singlenucleotide polymorphisms (SNPs) for association with asthma sever