TSG101 is not mutated in lung cancer but a shortened transcript is frequently expressed in small cell lung cancer
β Scribed by Fan, You Hong; Su, Li-Kuo; Hong, Waun Ki; Fong, Kwun M; Sekido, Yoshitaka S; Gazdar, Adi F; Minna, John D; Mao, Li; Oh, Yun; Proctor, Monja L
- Book ID
- 110061513
- Publisher
- Nature Publishing Group
- Year
- 1998
- Tongue
- English
- Weight
- 413 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0950-9232
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## Abstract Identification of a homozygous deletion in cancer cells provides strong evidence for the location of a tumor suppressor gene (TSG). We analyzed the 2p24 homozygous deletion of a nonβsmallβcell lung cancer (NSCLC) cell line, NCIβH2882, and found that the deletion size was 3.7 Mbp. Since