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TSG101 is not mutated in lung cancer but a shortened transcript is frequently expressed in small cell lung cancer

✍ Scribed by Fan, You Hong; Su, Li-Kuo; Hong, Waun Ki; Fong, Kwun M; Sekido, Yoshitaka S; Gazdar, Adi F; Minna, John D; Mao, Li; Oh, Yun; Proctor, Monja L


Book ID
110061513
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
413 KB
Volume
17
Category
Article
ISSN
0950-9232

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## Abstract Identification of a homozygous deletion in cancer cells provides strong evidence for the location of a tumor suppressor gene (TSG). We analyzed the 2p24 homozygous deletion of a non‐small‐cell lung cancer (NSCLC) cell line, NCI‐H2882, and found that the deletion size was 3.7 Mbp. Since