✦ LIBER ✦

Tryptophan metabolism and the occurrence of amino acids and serotonin in the leech (Hirudo medicinalis) nervous system

✍ Scribed by Karin Stenzel; Dr. Volker Neuhoff

Publisher: John Wiley and Sons
Year: 1976
Tongue: English
Weight: 575 KB
Volume: 2
Category: Article
ISSN: 0360-4012
DOI: 10.1002/jnr.490020102

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The occurrence and distribution of serotonin (5‐HT) and amino acids along the central nerve chain of the leech, Hirudo medicinalis, was analyzed using dansylchloride in order to obtain information on the functional roles of amines and amino acids. There was no statistical variation in the occurrence of most of the amino acids or serotonin in the different parts of the dorsal nerve chain of the leech. A variation in the serotonin content was found during the year with the highest level occurring in winter. Leech ganglia also accumulated ^3^H‐tryptophan and metabolized part of it to form 5‐HTP, 5‐HT, and 5‐HIAA. The resutls are discussed from the point of view of 5‐HT being a transmitter substance.

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