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Trypanosoma cruzi: Phosphatidylinositol 3-Kinase and Protein Kinase B Activation Is Associated with Parasite Invasion

โœ Scribed by S.E Wilkowsky; M.A Barbieri; P Stahl; E.L.D Isola


Book ID
115603912
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
210 KB
Volume
264
Category
Article
ISSN
0014-4827

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โœ Mohamed R. Sayed; Michael P. Sheid; Christiaan M. Stevens; Vincent Duronio ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 157 KB

In this study, we investigated the activation of a new member of the focal adhesion kinase family of tyrosine kinases, the proline-rich tyrosine kinase, or PYK2, in platelets. We show that PYK2 is tyrosine phosphorylated and its activity is increased during early stages of platelet aggregation. This