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Trypanocidal Sesquiterpenes from Lychnophora Species

✍ Scribed by Alaíde B. de Oliveira; Dênia A. Saúde; Katia S. P. Perry; Dâmaris S. Duarte; Délio S. Raslan; Maria Amélia D. Boaventura; Egler Chiari

Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
324 KB
Volume
10
Category
Article
ISSN
0951-418X

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✦ Synopsis

The bioguided fractionation of the crude extracts of Lychnophora passerina (Mart. ex DC) Gardn., L pinaster Mart. and L . hichocarpha Spreng. led to the isolation of four compounds active against the trypomastigote forms of Trypanosoma cruzi: the sesquiterpene lactones goyazensolide (l), eremantholide C (2), and lychnopholide (3) and a new caryophyllene derivative, which was named lychnophoic acid (4).

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