Truncated TrkB mediates the endocytosis
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Ralph F Alderson; Rory Curtis; Andrea L Alterman; Ronald M Lindsay; Peter S DiSt
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Article
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2000
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Elsevier Science
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English
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Binding and cross-linking studies with radiolabeled neurotrophins demonstrate that cultured rat hippocampal astrocytes lack full-length TrkB, but do express high levels of truncated TrkB (tTrkB). In astrocytes and Schwann cells, tTrkB appears to have the novel function of mediating the endocytosis o