TRPV4 channel activation improves the tensile properties of self-assembled articular cartilage constructs

Effects of confinement on the mechanical

Effects of confinement on the mechanical properties of self-assembled articular cartilage constructs in the direction orthogonal to the confinement surface

✍ Benjamin D. Elder; Kyriacos A. Athanasiou 📂 Article 📅 2008 🏛 Elsevier Science 🌐 English ⚖ 321 KB

## Abstract This study examined the effects of radial confinement and passive axial compression‐induced vertical confinement, on the biomechanical, biochemical, and histological properties of self‐assembled chondrocyte constructs. The self‐assembled constructs, engineered without the use of an exog