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TRPM6 expression and cell proliferation are up-regulated by phosphorylation of ERK1/2 in renal epithelial cells

✍ Scribed by Akira Ikari; Chiaki Okude; Hayato Sawada; Yasuhiro Yamazaki; Junko Sugatani; Masao Miwa

Book ID
116296547
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
326 KB
Volume
369
Category
Article
ISSN
0006-291X

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✍ Akira Ikari; Ayumi Sanada; Chiaki Okude; Hayato Sawada; Yasuhiro Yamazaki; Junko πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 297 KB

## Abstract Transient receptor potential melastatin 6 (TRPM6) channel is involved in the reabsorption of magnesium in the kidney. We recently found that TRPM6 expression is up‐regulated by EGF, but the regulatory mechanism has not been clear. TRPM6 mRNA was endogenously expressed in HEK293 cells. T