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TRPC1 channels regulate directionality of migrating cells

✍ Scribed by A. Fabian; T. Fortmann; P. Dieterich; C. Riethmüller; P. Schön; S. Mally; B. Nilius; A. Schwab

Publisher
Springer
Year
2008
Tongue
English
Weight
389 KB
Volume
457
Category
Article
ISSN
0031-6768

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✍ Albrecht Schwab; Andrea Wulf; Christoph Schulz; Wolfram Kessler; Volodymyr Nechy 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 315 KB

## Abstract Cell migration is crucial for wound healing, immune defense, or formation of tumor metastases. In addition to the cytoskeleton, Ca^2+^ sensitive K^+^ channels (IK1) are also part of the cellular “migration machinery.” We showed that Ca^2+^ sensitive K^+^ channels support the retraction