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Trp proteins form store-operated cation channels in human vascular endothelial cells

✍ Scribed by Klaus Groschner; Susanne Hingel; Birgit Lintschinger; Monika Balzer; Christoph Romanin; Xi Zhu; Wolfgang Schreibmayer


Book ID
117109847
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
183 KB
Volume
437
Category
Article
ISSN
0014-5793

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Endothelial cells obtained from human umbilical chord have been studied by the patch clamp method. An ion channel is described that is activated by microM concentrations of histamine and shows a slow run-down in cell-attached patches. After excision, channel activity quickly runs down to zero open p