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Trough levels and concentration time curves of cyclosporine in patients undergoing renal transplantation

โœ Scribed by Frey, Felix J; Horber, Fritz F; Frey, Brigitte M

Book ID
109844320
Publisher
Nature Publishing Group
Year
1988
Tongue
English
Weight
666 KB
Volume
43
Category
Article
ISSN
0009-9236

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After orthotopic liver transplantation (OLT) many patients use emulsified cyclosporine. Recent data showed that blood levels 2 hours after dosing (C-2) better reflect systemic exposure to the drug (area under the blood concentration time curve) than trough levels (C-0) do. We investigated difference