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Trough imatinib plasma levels are associated with both cytogenetic and molecular responses to standard-dose imatinib in chronic myeloid leukemia

✍ Scribed by Picard, S.; Titier, K.; Etienne, G.; Teilhet, E.; Ducint, D.; Bernard, M.-A.; Lassalle, R.; Marit, G.; Reiffers, J.; Begaud, B.; Moore, N.; Molimard, M.; Mahon, F.-X.


Book ID
121684340
Publisher
American Society of Hematology
Year
2006
Tongue
English
Weight
81 KB
Volume
109
Category
Article
ISSN
0006-4971

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✍ Massimo Breccia; Laura Cannella; Caterina Stefanizzi; Roberto Latagliata; Mauro πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 76 KB

## Abstract Imatinib mesylate is the gold standard treatment of chronic myeloid leukaemia (CML) and 400 mg/day is considered the standard dose. Although it is generally well tolerated, some patients require temporary drug discontinuation and permanent dose reduction because of haematological or non