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Troglitazone acutely activates AMP-activated protein kinase and inhibits insulin secretion from beta cells

โœ Scribed by Xiao Wang; Libin Zhou; Li Shao; Lei Qian; Xuelian Fu; Guo Li; Tianhong Luo; Yanyun Gu; Fengying Li; Jiping Li; Sheng Zheng; Min Luo


Book ID
116719119
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
327 KB
Volume
81
Category
Article
ISSN
0024-3205

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## Abstract The aim of this study was to investigate the acute effects of troglitazone on several pathways of glucose and fatty acid (FA) partitioning and the molecular mechanisms involved in these processes in skeletal muscle. Exposure of L6 myotubes to troglitazone for 1 h significantly increased