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tRNA selection and kinetic proofreading in translation

โœ Scribed by Blanchard, Scott C; Gonzalez, Ruben L; Kim, Harold D; Chu, Steven; Puglisi, Joseph D


Book ID
109966887
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
780 KB
Volume
11
Category
Article
ISSN
1545-9993

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tRNA selection and kinetic proofreading
โœ Blanchard, Scott C; Gonzalez, Ruben L; Kim, Harold D; Chu, Steven; Puglisi, Jose ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› Nature Publishing Group ๐ŸŒ English โš– 780 KB

Using single-molecule methods we observed the stepwise movement of aminoacyl-tRNA (aa-tRNA) into the ribosome during selection and kinetic proofreading using single-molecule fluorescence resonance energy transfer (smFRET). Intermediate states in the pathway of tRNA delivery were observed using antib

Recognition and selection of tRNA in tra
โœ Marina V. Rodnina; Kirill B. Gromadski; Ute Kothe; Hans-Joachim Wieden ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 219 KB
Kinetic Proofreading Scanning Models for
โœ XIPING BI; DIXIE J. GOSS ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 222 KB

Two simpli"ed kinetic proofreading scanning (KPS) models were proposed to describe the 5 cap and 3 poly(A) tail dependency of eukaryotic translation initiation. In Model I, the initiation factor complex starts scanning and unwinding the secondary structure of the 5 untranslated region (UTR) from the