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TrkB is highly expressed in NSCLC and mediates BDNF-induced the activation of Pyk2 signaling and the invasion of A549 cells

✍ Scribed by Siyang Zhang; Dawei Guo; Wenting Luo; Qingfu Zhang; Ying Zhang; Chunyan Li; Yao Lu; Zeshi Cui; Xueshan Qiu


Book ID
115010149
Publisher
BioMed Central
Year
2010
Tongue
English
Weight
561 KB
Volume
10
Category
Article
ISSN
1471-2407

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TGF-β–induced invasiveness of pancreatic
✍ Volker Ellenrieder; Sandra F. Hendler; Claudia Ruhland; Wolfgang Boeck; Guido Ad πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 French βš– 216 KB

TGF-beta strongly promotes local tumor progression in advanced epithelial tumors, though the underlying mechanisms are poorly understood. In the present study, we demonstrate the potential of TGF-beta to increase the invasiveness of the pancreatic cancer cell lines PANC-1 and IMIM-PC1. TGF-beta-indu