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TrkA receptors delay C6-2B glioma cell growth in rat striatum

✍ Scribed by Stuart J Rabin; Carlo Tornatore; Belinda Baker-Cairns; Giulio Spiga; Italo Mocchetti

Book ID
117387085
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
530 KB
Volume
56
Category
Article
ISSN
0169-328X

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✍ Beth R. Pflug; Anna Maria Colangelo; Carlo Tornatore; Italo Mocchetti πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 252 KB

## Abstract Nerve growth factor (NGF) binds to the TrkA tyrosine kinase and the p75 neurotrophin receptors. Depending upon which receptor is activated, NGF can induce differentiation or apoptosis. C6‐2B glioma cells express the p75 receptor, but NGF decreases their growth only when TrkA is introduc