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Trk kinase inhibitors as new treatments for cancer and pain

✍ Scribed by Wang, Tao; Yu, Dingwei; Lamb, Michelle L


Book ID
121456873
Publisher
Informa plc
Year
2009
Tongue
English
Weight
663 KB
Volume
19
Category
Article
ISSN
1354-3776

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Glycogen synthase kinase 3 (GSK-3) was initially described as a key enzyme involved in glycogen metabolism, but is now known to regulate a diverse array of cell functions. Two forms of the enzyme, GSK-3alpha and GSK-3beta, have been previously identified. Small molecules inhibitors of GSK-3 may, the