Triumfettosterol Id and Triumfettosaponin, a New (Fatty Acyl)-Substituted Steroid and a Triterpenoid ‘Dimer’ Bis(β-D-glucopyranosyl) Ester from the Leaves of Wild Triumfetta cordifolia A. Rich. (Tiliaceae)
✍ Scribed by Louis Pergaud Sandjo; Ingrid Konga Simo; Victor Kuete; Paul Hannewald; Mehdi Yemloul; Vincent Rincheval; Bonaventure Tchaleu Ngadjui; Gilbert Kirsch; François Couty; Serge Schneider
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- German
- Weight
- 259 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0018-019X
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✦ Synopsis
Abstract
Two new triterpenoid derivatives were isolated from the leaves of wild Triumfetta cordifolia A. Rich. and identified to be a (fatty acyl)‐substituted steroid 1 and a triterpenoid saponin ‘dimer’ 2, named (3__β__)‐stigmasta‐5,22‐diene‐3,29‐diol 3‐propanoate 29‐triacontanoate and (2__α__,3__β__,19__α__)‐2,3,19‐trimethoxyurs‐12‐ene‐24,28‐dioic acid 24‐[(2__α__,3__β__)‐24,28‐bis(β‐D‐glucopyranosyloxy)‐2‐hydroxy‐24,28‐dioxours‐12‐en‐3‐yl] ester, respectively. These compounds were obtained together with a mixture of known sterols (stigmasterol/β‐sitosterol=(3__β__,22__E__)‐stigmasta‐5,22‐dien‐3‐ol/(3__β__)‐stigmast‐5‐en‐3‐ol) and trans‐tiliroside (3). The structures 1 and 2 were determined on the basis of NMR data (^1^H‐, ^13^C‐, and 2D‐NMR analyses) and mass spectrometry and confirmed by chemical transformations. The antimicrobial activities of trans‐tiliroside (3) against eight bacterial and two fungal strains were evaluated. This compound showed weak activities on some bacterial strains.