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Tritium nuclear magnetic resonance spectroscopy. Part 11. Further consideration of referencing, isotope effects and coupling constants: Preparation of [3H]tetramethylsilane

✍ Scribed by James P. Bloxsidge; John A. Elvidge; John R. Jones; Ramachandra B. Mane; Manouchehr Saljoughian


Publisher
John Wiley and Sons
Year
1979
Tongue
English
Weight
459 KB
Volume
12
Category
Article
ISSN
0749-1581

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✦ Synopsis


Abstract

Small discrepancies between ^3^H and ^1^H chemical shifts in organic compounds led to the finding that the ratio of Larmor frequencies ω~T~/ω~H~ depends on the carbon‐hydrogen bond hybridisation. The ‘best’ ratio for ghost referencing of ^3^H NMR spectra was then determined from measurements on purified partially tritiated TMS as 1.066639738±2 × 10^−9^. Some ^3^H isotope effects on chemical shifts are listed and the ^3^H isotope effect on the methylene geminal coupling constant in benzyl methyl sulphoxide is measured. Use of ^2^H in the measurement of ^2^J(HH) coupling constants has inherent disadvantages, overcome by use of ^3^H substitution.