✦ LIBER ✦
Tritium Labelling of Cyprodime ( = (—)-17-(Cyclopropylmethyl)-4,14-dimethoxymorphinan-6-one), a μ Receptor-Selective Opioid Antagonist
✍ Scribed by Ferenc Ötvös; Géza Tóth; Helmut Schmidhammer
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- German
- Weight
- 169 KB
- Volume
- 75
- Category
- Article
- ISSN
- 0018-019X
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✦ Synopsis
Abstract
The preparation of [1‐^3^H]cyprodime (2), which has a specific activity of 31.6 Ci/mmol was carried out by catalytic tritiodehalogenation of 1‐bromocyprodime (3). Bromination of cyprodime was performed by using chloroperoxidase, KBr, and H~2~O~2~.