Triterpenoids from Eucalyptus camaldulensisDehnh. Tissue Cultures
✍ Scribed by Dimitroula Tsiri; Nektarios Aligiannis; Konstantia Graikou; Caroline Spyropoulos; Ioanna Chinou
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- German
- Weight
- 165 KB
- Volume
- 91
- Category
- Article
- ISSN
- 0018-019X
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
A chemical study on tissue cultures from leaves and flowers of E. camaldulensis Dehnh. afforded the new natural product (2__α__,3__β__)‐2,3,23‐trihydroxy‐13,28‐epoxyurs‐11‐en‐28‐one (dryobalanolide) together with the known pentacyclic triterpenoids: betulinic acid, oleanolic acid, ursolic acid, (2__α__,3__β__)‐2,3,23‐trihydroxyolean‐12‐en‐28‐oic acid (arjunolic acid), (2__α__,3__β__)‐2,3,23‐trihydroxyurs‐12‐en‐28‐oic acid (asiatic acid), (2__α__)‐2‐hydroxyursolic acid, (2__α__)‐2‐hydroxyoleanolic acid (maslinic acid), as well as β‐sitosterol. The extracts and the isolated compounds were evaluated against eleven human pathogenic microorganisms, exhibiting a very interesting antibacterial spectrum of activities.
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The incorporation of [1-(14)C]acetate and [2(14) C]mevalonate into free and esterified triterpen-3-ols was examined in original plant organs and tissue cultures of Glycyrrhiza glabra var. glandulifera. Both substrates labeled β-amyrin, an oleanane-type triterpene, and cycloartenol and 24-methylenecy