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Tristetraprolin down-regulates IL-23 expression in colon cancer cells

✍ Scribed by Lee, Hyun Hee; Yang, Song Soo; Vo, Mai-Tram; Cho, Wha Ja; Lee, Byung Ju; Leem, Sun-Hee; Lee, Sang-Hyun; Cha, Hee Jeong; Park, Jeong Woo


Book ID
121586464
Publisher
Korean Society for Molecular and Cellular Biology
Year
2013
Tongue
English
Weight
424 KB
Volume
36
Category
Article
ISSN
1016-8478

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## Abstract Tristetraprolin (TTP) is an AU‐rich element‐binding protein that regulates mRNA stability. Here, we report that TTP suppress the growth of human colon cancer cells both __in vivo__ and __in vitro__ by regulating of the expression of vascular endothelial growth factor (VEGF). TTP protein