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Trisomy 5 and loss of the Y chromosome as the sole cytogenetic anomalies in a cavernous hemangioma/angiosarcoma

✍ Scribed by Dr. Nils Mandahl; Yuesheng Jin; Sverre Heim; Helena Willén; Johan Wennerberg; Anders Biörklund; Felix Mitelman

Book ID
102220762
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
289 KB
Volume
1
Category
Article
ISSN
1045-2257

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✦ Synopsis

Cytogenetic analysis of a cavernous hemangioma with transition to angiosarcoma revealed the mosaic karyotype 47,XY,+ 5/46,X, -Y ,+ 5/45,X, -Y/46,XY. No cytogenetically analyzed hemangiomas or angiosarcomas have been reported before.

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Y-chromosome loss as the sole karyotypic
Y-chromosome loss as the sole karyotypic anomaly with 3′RARα submicroscopic deletion in a case of M3r subtype of acute promyelocytic leukemia
✍ Yongsheng Han; Yongquan Xue; Jun Zhang; Jinlan Pan; Yafang Wu; Shuxiao Bai 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 316 KB

Acute promyelocytic leukemia (APL) is characterized by the presence of a chromosomal rearrangement involving retinoic acid receptor alpha (RARalpha) gene generating the X-RARalpha fusion. We describe here a unique RARalpha gene rearrangement in a patient with M3r subtype of APL. Conventional cytogen