✦ LIBER ✦
Trisomy 2, trisomy 20, and del(17p) as sole chromosomal abnormalities in three cases of hepatoblastoma
✍ Scribed by Vijay S. Tonk; Kathleen S. Wilson; Charles F. Timmons; Nancy R. Schneider
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 693 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1045-2257
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✦ Synopsis
Short
-term cultures of three hepatoblastomas were analyzed cytogenetically. Trisomy 2, trisomy 20, and a deletion of I7p were found as the sole abnormalities, yielding the karyotypes 47,XY, + 2 47,XX, + 20; and 46,XX,del( I7)(p I2)/46,XX. This is the first reported case of deletion of 17p as the sole chromosomal abnormality in a hepatoblastoma and the first reported case of trisomy 20 without double minute chromosomes as a sole chromosomal abnormality in hepatoblastoma. Genes Chromosom Concer I I : 199-202 (1994). 0 I994 Wiley-Liss, Inc.