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Trisomy 11 in myelodysplastic syndrome-derived acute myeloblasts leukaemias

✍ Scribed by Gian Carlo Avanzi; Bruna Giovinazzo; Arturo Rosso; Lorella Depaoli; Marilena Bertini; Luigi Resegotti; Luigi Pegoraro


Book ID
114791061
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
399 KB
Volume
43
Category
Article
ISSN
0902-4441

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Tandem duplication of theMLL gene in mye
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Trisomy 11 as a sole chromosomal abnormality is a rare aberration observed in myelodysplastic syndrome (MDS) or acute myeloblastic leukemia (AML). Recently a partial tandem duplication of the MLL gene, located on chromosome band 11q23, has been identified in de novo AML with trisomy 11. We describe