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Triptolide (PG-490) induces apoptosis of dendritic cells through sequential p38 MAP kinase phosphorylation and caspase 3 activation

✍ Scribed by Qiuyan Liu; Taoyong Chen; Huabiao Chen; Minghui Zhang; Nan Li; Zhanjun Lu; Pengcheng Ma; Xuetao Cao


Book ID
116288499
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
436 KB
Volume
319
Category
Article
ISSN
0006-291X

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## Abstract Our previous study showed that cobalt chloride (CoCl~2~) could induce PC12 cell apoptosis and that the CoCl~2~‐treated PC12 cells may serve as a simple in vitro model for the study of the mechanism of hypoxia‐linked neuronal disorders. The aim of this study is to elucidate the mechanism