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Triptolide augments the effects of 5-lipoxygenase RNA interference in suppressing pancreatic tumor growth in a xenograft mouse model

✍ Scribed by Xiaoling Ding; Xiaorong Zhou; Haifeng Zhang; Jingdan Qing; Hui Qiang; Guoxiong Zhou

Book ID
105993744
Publisher
Springer
Year
2011
Tongue
English
Weight
621 KB
Volume
69
Category
Article
ISSN
0344-5704

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## Abstract Proteinase‐activated receptor‐2 (PAR‐2), which is a G protein‐coupled receptor, is activated in inflammatory processes and cell proliferation. We previously demonstrated that an anti‐PAR‐2 antibody suppresses proliferation of human pancreatic cells __in vitro__. However, there have been