Triple combination of retinoic acid plus actinomycin D plus dimethylformamide induces differentiation of human acute myeloid leukaemic blasts in primary culture

Triple combination of retinoic acid + lo

Triple combination of retinoic acid + low concentration of cytosine arabinoside + hexamethylene bisacetamide induces differentiation of human aml blasts in primary culture

✍ Dr. H. T. Hassan; J. K. H. Rees 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 730 KB

Differentiation induction therapy provides an alternative therapeutic approach for patients with acute myeloid leukemia (AML) who are either unsuitable for or unresponsive to conventional cytotoxic chemotherapy. The effect of a triple combination of retinoic acid (RA) + low concentration of cytosine