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Trinucleotide repeats and neuropsychiatric disorders

โœ Scribed by K. Taranath Shetty; Rita Christopher


Publisher
Association of Clinical Biochemistry of India
Year
2000
Tongue
English
Weight
749 KB
Volume
15
Category
Article
ISSN
0970-1915

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Huntington's disease (HD) is a neurodegenerative disorder associated with expansion of CAG trinucleotide repeats in the huntingtin gene. A minimum of 36 CAG repeats is usually reported in patients with clinical features of HD; 30 to 35 repeats represent an intermediate range. Here we report a 65-yea