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Trimethylaminuria (fish-odour syndrome) and oral malodour

✍ Scribed by SC Mitchell

Book ID: 111271904
Publisher: John Wiley and Sons
Year: 2005
Tongue: English
Weight: 89 KB
Volume: 11
Category: Article
ISSN: 1354-523X
DOI: 10.1111/j.1601-0825.2005.01081.x

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Trimethylaminuria is inherited recessively as a defect in hepatic N-oxidation of dietary derived trimethylamine (TMA) which causes excess excretion of TMA so that affected individuals have a body odour resembling rotten fish. Flavin-containing mono-oxygenase 3 (FMO3) catalyses TMA oxidation and muta