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Trimethoprim pharmacokinetics in children with renal insufficiency

✍ Scribed by Hoppu, Kalle; Koskimies, Olli; Tuomisto, Jouko

Book ID
109844121
Publisher
Nature Publishing Group
Year
1987
Tongue
English
Weight
522 KB
Volume
42
Category
Article
ISSN
0009-9236

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✍ A. Leroy; J. P. Fillastre; I. Etienne; F. Borsa-LebΓ‘s; G. Humbert πŸ“‚ Article πŸ“… 1992 πŸ› Springer 🌐 English βš– 379 KB

The pharmacokinetics of IV meropenem (500 mg over 30 min) has been studied in 6 healthy volunteers and 26 patients with various degrees of renal impairment. Blood samples were taken at different times over 24 h in healthy subjects and 36 to 48 h in uraemic patients, and four or five urine samples we