In this report, three new cases of trilateral retinoblastoma are presented. The clinical presentation, treatment, and outcome of the patients are described and compared with those of 32 cases that have been previously reported in the literature. A positive family history was obtained in 68% of the p
Trilateral retinoblastoma: A report of five patients
โ Scribed by Winfried M. K. Amoaku; Harry E. Willshaw; Sheila E. Parkes; Kishore J. Shah; Jillian R. Mann
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 586 KB
- Volume
- 78
- Category
- Article
- ISSN
- 0008-543X
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โฆ Synopsis
BACKGROUND.
Trilateral retinoblastoma is a well recognized. although rare, syndrome. Most of the reported cases have involved a family history of retinoblastoma (KB) and the diseasc is almost always fatal. The authors chose to investigate the cases of trilateral reiinoblastoma occurring in the West Midlands, a region of the llnited Kingdom with an increasing incidence of bilateral sporadic RE. METHODS. Five patients with trilateral retinoblastoma (including two were previously reported), diagnosed in 146 consecutive patients with RE in the West Midlands Health Authority Region between 1957 and 1994, are presented (an incidence of 3%). Their clinical presentation, treatment, and outcome are descrihed.
๐ SIMILAR VOLUMES
Seventy-two patients with retinoblastoma (RTB) (unilateral (47 patients] and bilateral [25 patients]) were studied for a period of 6 years. Treatment consisted of enucleation of those eyes that had severe involvement and was followed by radiation therapy and/or chemotherapy (systemic or intrathecal)