Reduced MPTP neurotoxicity in striatum o
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Michael R. Kilbourn; Phillip Sherman; Louise C. Abbott
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Article
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1998
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John Wiley and Sons
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English
β 83 KB
The effects of MPTP treatment (4 Ο« 10 mg/kg, 2-h intervals) on in vivo striatal binding of (Ο©)-β£-[ 3 H]dihydrotetrabenazine ((Ο©)-[ 3 H]DTBZ) to the vesicular monoamine transporter type 2 (VMAT2) were examined in wild type (Ο©,Ο©) and tottering (tg/tg) mice of the C57BL/6J strain. The tottering mutant