Trifluoromethylation of enamines under acidic conditions
β Scribed by Roman T. Gritsenko; Vitalij V. Levin; Alexander D. Dilman; Pavel A. Belyakov; Marina I. Struchkova; Vladimir A. Tartakovsky
- Book ID
- 108285519
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- French
- Weight
- 629 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0040-4039
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## Abstract A general method for the trifluoromethylation of imines by using Me~3~SiCF~3~ under acidic conditions is described. The reaction is promoted by hydrofluoric acid generated in situ from KHF~2~ and either TFA or TfOH. A new chemoselectivity pattern was achieved, as the C=N bond was found
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