Triethylenethiophosphoramide (Thio-TEPA) in the treatment of neoplastic disease
โ Scribed by John E. Ultmann; George A. Hyman; Charles Crandall; Horst Naujoks; Alfred Gellhorn
- Publisher
- John Wiley and Sons
- Year
- 1957
- Tongue
- English
- Weight
- 785 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0008-543X
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HE MANAGEMENT of hypercalcemia often T constitutes a major medical problem in patients with cancer. Hypercalcemia has been described as a complication of disseminated cancer in bones. 1 ~1 2 . \* and more recently as a complication of cancer in which no invasion of bone can be demonstrated.'. 19 Si
Forty-six patients with superficial transitional cell carcinoma of the bladder were randomized into two groups. Thio-TEPA or adriamycin were instilled periodically into the bladder and cystoscopic follow up was carried out. Both thio-TEPA and adriamycin proved to have similar efficacy in delaying tu