Triethylborane as an efficient promoter for palladium-catalyzed allylation of active methylene compounds with allyl alcohols

✍ Scribed by Masanari Kimura; Ryutaro Mukai; Naoko Tanigawa; Shuji Tanaka; Yoshinao Tamaru

• Book ID: 104205741
• Publisher: Elsevier Science
• Year: 2003
• Tongue: French
• Weight: 332 KB
• Volume: 59
• Category: Article
• ISSN: 0040-4020
• DOI: 10.1016/s0040-4020(03)01234-1

✦ Synopsis

Without prior activation of allyl alcohols, allylation of a variety of active methylene compounds with allyl alcohols proceeds smoothly at rt -508C in the presence of catalytic amounts of Pd(OAc) 2 (1 -10 mol%), Et 3 B (30 -240 mol%), a phosphine ligand (1 -20 mol%), and a base (0 to 50 -60 mol%).