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Triclosan reduces microsomal prostaglandin E synthase-1 expression in human gingival fibroblasts

✍ Scribed by M. Mustafa; B. Wondimu; T. Yucel-Lindberg; A. T. Kats-Hallström; A. S. Jonsson; T. Modéer


Book ID
109359499
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
131 KB
Volume
32
Category
Article
ISSN
0303-6979

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Expression of microsomal prostaglandin E
✍ M. Westman; M. Korotkova; E. af Klint; A. Stark; L. P. Audoly; L. Klareskog; A.- 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 372 KB

Objective. Microsomal prostaglandin E synthase 1 (mPGES-1) catalyzes the formation of PGE 2 from cyclooxygenase-derived PGH 2 . Microsomal PGES-1 is induced by proinflammatory cytokines and is strongly linked to conditions that result in high PGE 2 biosynthesis. PGE 2 contributes to the pathogenesis