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Trichostatin A induces 5-lipoxygenase promoter activity and mRNA expression via inhibition of histone deacetylase 2 and 3

✍ Scribed by Laura Pufahl; Careen Katryniok; Nicole Schnur; Bernd L. Sorg; Julia Metzner; Manuel Grez; Dieter Steinhilber


Book ID
119857565
Publisher
Carol Davila University of Medicine Bucharest, Romania
Year
2012
Tongue
English
Weight
404 KB
Volume
16
Category
Article
ISSN
1582-1838

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## Abstract Aberrant janus kinase/signal transducers and activators of transcription (JAK/STAT) signaling is involved in the oncogenesis of several cancers. Suppressors of cytokine signaling (SOCS) genes and SH2‐containing protein tyrosine phosphatase 1 (SHP1) proteins, which are negative regulator