𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Trichostatin a, a histone deacetylase inhibitor stimulateCYP3A4proximal promoter activity in hepa-I cells

✍ Scribed by Mee Ryung Ahn; Dae-Kee Kim; Yhun Yhong Sheen

Publisher
Springer
Year
2004
Tongue
English
Weight
993 KB
Volume
27
Category
Article
ISSN
0253-6269

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Trichostatin A, a histone deacetylase in
Trichostatin A, a histone deacetylase inhibitor, suppresses JAK2/STAT3 signaling via inducing the promoter-associated histone acetylation of SOCS1 and SOCS3 in human colorectal cancer cells
✍ Hua Xiong; Wan Du; Yan-Jie Zhang; Jie Hong; Wen-Yu Su; Jie-Ting Tang; Ying-Chao πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 882 KB

## Abstract Aberrant janus kinase/signal transducers and activators of transcription (JAK/STAT) signaling is involved in the oncogenesis of several cancers. Suppressors of cytokine signaling (SOCS) genes and SH2‐containing protein tyrosine phosphatase 1 (SHP1) proteins, which are negative regulator

A histone deacetylase inhibitor, trichos
A histone deacetylase inhibitor, trichostatin A, suppresses myofibroblastic differentiation of rat hepatic stellate cells in primary culture
✍ Toshiro Niki; Krista Rombouts; Pieter De Bleser; Karen De Smet; Vera Rogiers; De πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 543 KB

Hepatic stellate cells are the major cellular sources of extracellular matrix in chronic liver diseases leading to fibrosis. We explored the antifibrogenic effect of two histone deacetylase inhibitors, sodium butyrate and trichostatin A (TSA), on this cell type in vitro. Primary hepatic stellate cel

Histone deacetylase inhibitor trichostat
Histone deacetylase inhibitor trichostatin a induces cell-cycle arrest/apoptosis and hepatocyte differentiation in human hepatoma cells
✍ Yo-ichi Yamashita; Mitsuo Shimada; Norifumi Harimoto; Tatsuya Rikimaru; Ken Shir πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 French βš– 212 KB πŸ‘ 1 views

## Abstract Remodeling of the chromatin template by inhibition of HDAC activities represents a potential transcriptional therapy for neoplastic disease. A number of HDAC inhibitors that modulate __in vitro__ cell growth and differentiation have been developed. We analyzed the effects of TSA, a spec

Reduction of telomerase activity in huma
Reduction of telomerase activity in human liver cancer cells by a histone deacetylase inhibitor
✍ Mitsuyasu Nakamura; Hidetsugu Saito; Hirotoshi Ebinuma; Kanji Wakabayashi; Yoshi πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 322 KB

## Abstract The presence of telomerase has been demonstrated recently in many different malignancies. Several reports documented that in human hepatocellular carcinoma, the level of telomerase activity parallels its differentiation stage. In the present study, the effect of the differentiation‐indu