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Triazolodiazepines: dissociation of their Paf (platelet activating factor) antagonistic and CNS activity

โœ Scribed by J. Casals-Stenzel; K.H. Weber

Book ID
117958730
Publisher
Nature Publishing Group
Year
1987
Tongue
English
Weight
903 KB
Volume
90
Category
Article
ISSN
0007-1188

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Platelet-activating factor (PAF) is an autacoid derived from cellular membrane phospholipids in response to chemical or physical stimuli. It has been identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphocholine; the alkyl group is composed of 16 or 18 carbon atoms in human cells. PAF can cause a se