Triazinobenzothiazine — A New Heterocyclic System via a Novel Cyclization Reaction
✍ Scribed by H. Musser, John; C. Lewis, Susan; H. W. Bender, Reinhold
- Book ID
- 115523048
- Publisher
- Japan Institute of Heterocyclic Chemistry
- Year
- 1990
- Tongue
- English
- Weight
- 82 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0385-5414
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📜 SIMILAR VOLUMES
In the course of our search for biologically active agents, we discovered a novel heterocyclizatinn reaction. We wish to report details of the reaction and then comment on possible mechanisms implicated in the cyclization. When an aqueous solution of 7-methyl-7-azabicycloL4.l.O]heptane (1) and 2 eq
Isoflavone derivatives were synthesized via intramolecular cyclization of 3-(2-bromophenyl)-3oxopropanal derivatives, using CuI as the catalyst, 2-picolinic acid (¼ pyridine-2-carboxylic acid) as the ligand, K 2 CO 3 as the base, and DMF as the solvent, in up to 96% yield. The synthesis is functiona