๐”– Bobbio Scriptorium
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Triazines and related products. Part XVI. Synthesis of triazolotriazines by cyclisation of 3-hydrazino-1,2,4-triazines and 3-hydrazino-1,2,4-triazoles

โœ Scribed by Gray, Elizabeth Jane; Stevens, Malcolm F. G.


Book ID
118151388
Publisher
Royal Society of Chemistry
Year
1976
Weight
558 KB
Volume
14
Category
Article
ISSN
1472-7781

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To develop nonacidic, nonsteroidal anti-inflammatory agents without GI complications, a series of asymmetric triazines was synthesized and evaluated for anti-inflammatory efficacy in the carrageenan-induced pedal edema assay. Toxicity was estimated by determination of approximate LD50 values in mice