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Triaryl (Z)-olefins suitable for radiolabeling with iodine-124 or fluorine-18 radionuclides for positron emission tomography imaging of estrogen positive breast tumors

✍ Scribed by Khaled R.A. Abdellatif; Carlos A. Velázquez; Zhangjian Huang; Morshed A. Chowdhury; Edward E. Knaus

Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
257 KB
Volume
21
Category
Article
ISSN
0960-894X

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✦ Synopsis

Tricyclic (Z)

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Triaryl (Z)-olefins suitable for radiola
Triaryl (Z)-olefins suitable for radiolabeling with carbon-11 or fluorine-18 radionuclides for positron emission tomography imaging of cyclooxygenase-2 expression in pathological disease
✍ Khaled R.A. Abdellatif; Carlos A. Velázquez; Zhangjian Huang; Morshed A. Chowdhu 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 345 KB

A group of (Z)-1,1-diphenyl-2-(4-methylsulfonylphenyl)alk-1-enes were synthesized using methodologies that will allow incorporation of a [ 11 C]OCH 3 substituent at the para-position of the C-1 phenyl ring, a [ 11 C]SO 2 CH 3 substituent at the para-position of the C-2 phenyl ring, a [ 18 F]OCH 2 CH