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TRIAD1 inhibits MDM2-mediated p53 ubiquitination and degradation

✍ Scribed by Seunghee Bae; Jin Hyuk Jung; Karam Kim; In-Sook An; Soo-Yeon Kim; Jae Ho Lee; In-Chul Park; Young-Woo Jin; Su-Jae Lee; Sungkwan An

Book ID
118442909
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
985 KB
Volume
586
Category
Article
ISSN
0014-5793

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## Abstract Cross‐talk between the two transcription factors, p53 and hypoxia inducible factor 1Ξ± (HIF1A), is important in different pathophysiological conditions (Hammond and Giaccia, 2006, Clin Cancer Res 12:5007–5009) such as in the transition from myocardial hypertrophy to cardiac dilatation an