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Triad-DNA: a model for trinucleotide repeats

✍ Scribed by Kuryavyi, Vitaly V.; Jovin, Thomas M.


Book ID
109915692
Publisher
Nature Publishing Group
Year
1995
Tongue
English
Weight
468 KB
Volume
9
Category
Article
ISSN
1061-4036

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Recently, unstable trinucleotide repeats have been shown to be the etiologic factor in seven neuropsychiatric diseases, and they may play a similar role in other genetic disorders which exhibit genetic anticipation. We have tested one polymerase chain reaction (PCR)-based and two hybridizationbased