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TrfA dimers play a role in copy-number control of RK2 replication

✍ Scribed by Aresa E Toukdarian; Donald R Helinski


Book ID
117523271
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
261 KB
Volume
223
Category
Article
ISSN
0378-1119

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Dimerization of human pS2 (TFF1) plays a
✍ Marchbank, Tania; Westley, Bruce R.; May, Felicity E. B.; Calnan, Denis P.; Play πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 209 KB

Human pS2 (trefoil factor family 1, TFF1), a 60-amino acid member of the trefoil peptide family, forms dimers via Cys 58 and may stimulate gut repair. The effects of dimeric pS2-TFF1 and monomeric pS2-TFF1 (Cys 58 replaced by Ser 58 ) were compared in models of wound healing. Rats given dimeric pS2-